The present study examined the effect of bio-fertilizers on growth of cauliflower (Brassica oleracea L. var. botrytis) cv. Pusa Snowball K-1. The study was conducted during Rabi 2015-2016 at Horticulture Research Farm, Department of Horticulture, Babasaheb Bhimrao Ambedkar University, Lucknow, Uttar Pradesh. The treatment combination of bio-fertilizers was studied with different doses as T₁ (Control), T₂ (FYM, 20 t/ha.), T₂ (Vermicompost, 5 t/ha.), T₄ (Azotobacter, 2 kg/ha.), T₅ (PSB, 2 kg/ha.), T₆ (Neem Cake, 10 t/ha.), T₇ (FYM + Vermicompost, 5 t/ha.), T₈ (FYM + Azotobacter), T₉ ( FYM + PSB), T₁₀ ( FYM + Neem Cake), T₁₁ (FYM + Vermicompost + Azotobacter) and T₁₂ (FYM + Vermicompost +Azotobacter + PSB). Cauliflower growth including yield and quality parameters i.e. curd weight (g), curd diameter (cm), length of stalk (cm), yield per plot (kg), yield (q/ha) ascorbic acid and acidity respectively. Significant differences were observed for all the above mentioned parameters across the biofertilizer doses in cauliflower under Lucknow conditions.