An experiment was conducted to study the pattern of inheritance of vine length, fruits per plant, fruit weight and yield per plant from six generations (P₁, P₂ , F₁, F₂ , B₁ and B₂) means of ten crosses obtained by crossing nine inbred in ash gourd. Majority of the crosses indicated the contribution of dominance gene effects and duplicate epistasis. Among epistasis interactions, addictive x additive (i) played a significant role for vine length, fruits per plant and fruit weight, while additive x additive (i) and dominance x dominance (1) contributed towards fruit yield. These results suggest that heterosis breeding might be more effective for speedy improvement of this crop.