The fertigation plays very important role in successful cultivation of horticultural crops and enhance yield & minimize environmental pollution. The fertilizer use efficiency of N, P & K increased under fertigation in comparison to conventional fertilizer application with surface irrigation. The economics of tomato fertigation for major nutrients (N, P & K) for recommended dose of fertilizer N: P: K: : 111:67:133 kg/ha is calculated for various treatments i.e., T1 (conventional fertilizer application), T2 (N through fertigation and P & K through conventional fertilizer application), T3 (N & P through fertigation and K through conventional fertilizer application), T4 (N & K through fertigation and P through conventional fertilizer application) and T5 (N, P, & K through fertigation). The fertilizer cost for various treatment conditions varies between around Rs. 8418 to 42, 703 for different fertilizer sources conventional and water soluble considered in this study.